3-Nitro pretomanid

SL-9809

3-Nitro pretomanid, >98%

CAS No. : [1131004-99-3]

IUPAC Name : (S)-3-Nitro-6-((4-(trifluoromethoxy)benzyl)oxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine

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5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
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Applications : This is an impurity of Pretomanid, which is an anti-tuberculosis agent that inhibits the synthesis of protein and cell wall lipid; exhibits bactericidal activity against both replicating and static M. tuberculosis (MIC: 0.015-0.25 ug/mL); shows potent bactericidal activity against MDR M. tuberculosis and promising oral activity in animal infection models.

References : Stover C. K. et al.: Nature 405(6789), 962-66, 2000; Lenaerts A. J. et al.: Antimicrob Agents Chemother., 49(6), 2294-301, 2005; Manjunatha U. H. et al.: Antimicrob Agents Chemother., 50(10), 3350-354, 2006; Palmer D. B. et al.: J. Med. Chem., 58(7), 3036-3059, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.