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4-(3-((Allyloxy)methyl)phenyl)-2-chloropyrimidine

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4-(3-((Allyloxy)methyl)phenyl)-2-chloropyrimidine, >98%

CAS No. : [937273-29-5]

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
25MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
50MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
100MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
250MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
500MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C14H13ClN2O
Mol. Weight :
260.72
Appearance :
Light brown gum
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the synthesis of Pacritinib and related analogs. Pacritinib is an oral tyrosine kinase inhibitor that selectively targets Janus kinase 2 (JAK2) and Fms-like tyrosine kinase 3 (FLT3). It is currently being developed as a treatment option for intermediate and high risk myelofibrosis.

References : Hart S. et al.: Leukemia, 25(11), 1751-9, 2011; Hart S. et al.: Blood Cancer J. 1(11), e44, 2011; Komrokji R. S. et al.: Blood, 125(17), 2649-55, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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