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4,4,4-Trifluoro-1-(p-tolyl)butane-1,3-dione

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SL-4717

4,4,4-Trifluoro-1-(p-tolyl)butane-1,3-dione, >98%

CAS No. : [720-94-5]

MDL No. : MFCD00517909

IUPAC Name : 1-(4-Methylphenyl)-4,4,4-trifluorobutane-1,3-dione

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
1G8.00
In Stock  Estimated to ship on 20 September 2026
5G10.00
In Stock  Estimated to ship on 20 September 2026
25G20.00
In Stock  Estimated to ship on 20 September 2026
100G50.00
In Stock  Estimated to ship on 20 September 2026
500G155.00
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C11H9F3O2
Mol. Weight :
230.19
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of Celecoxib and related analogs. Celecoxib is a COX-2 selective nonsteroidal anti-inflammatory drug. It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis.

References : Penning T. D. et al.: J. Med. Chem., 40(9), 1347-1365, 1997; Liu D. B. et al.: Acta Pharmacol Sin., 33(5), 682-690, 2012; Hunter N. R. et al.: Int J. Radiat Oncol Biol Phys., 85(2), 472-476, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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