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4-(4-Amino-1,2,5-oxadiazol-3-yl)-3-(3-bromo-4-fluorophenyl)oxazol-2(3H)-one

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SI-7223

4-(4-Amino-1,2,5-oxadiazol-3-yl)-3-(3-bromo-4-fluorophenyl)oxazol-2(3H)-one, >98% (HPLC)

CAS No. : [914471-43-5]

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Chemical Properites
Mol. Formula :
C11H6BrFN4O3
Mol. Weight :
341.1
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a heteroaryl oxazolone derivative incorporating a 4‑amino‑1,2,5‑oxadiazole moiety and a 3‑bromo‑4‑fluorophenyl substituent. The scaffold combines strong electron‑deficient heterocycles with a halogen‑rich aryl group, making it a versatile structure for kinase inhibitor, enzyme modulator, or fragment‑based lead development. Its compact, polarity‑balanced framework is suitable for SAR exploration across oncology and inflammation‑related targets.

References : Wang K. et al.: J. Med. Chem., 66(1), 1027-1047, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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