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4,5-alpha-Dihydronorethisterone

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4,5-alpha-Dihydronorethisterone, >98%

CAS No. : [52-79-9]

Synonyms : 17α-Ethynyl-17β-hydroxy-5α-estran-3-one; Dihydro norethindrone (mixture of isomers); NSC 85401; STS 737

IUPAC Name : (5S,8R,9R,10S,13S,14S,17R)-17-Ethynyl-17-hydroxy-13-methylhexadecahydro-3H-cyclopenta[a]phenanthren-3-one

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Chemical Properites
Mol. Formula :
C20H28O2
Mol. Weight :
300.44
Appearance :
White to Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Norethindrone, which is a synthetic progestin, that mimic the actions of the endogenous ovarian hormone progesterone.

References : Schindler A. E. et al.: Maturitas, 46 Suppl 1, S7-S16, 2003; Schoonen W. G. et al.: J. Steroid Biochem Mol Biol, 74(4), 213-222, 2000; .Seeger H. et al.: J. Br. Menopause Soc, 9(1), 36-38, 2003; Enruez J. et al.: J. Endocrinol, 193(3), 493-50, 2007; Bain S. D. et al.: J. Bone Miner Res, 8(2), 219-230, 1993; Broul P. D. et al. Prague Med Rep, 107(4), 401-40, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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