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4-((5-Chloro-4-(((1s,4S)-4-hydroxy-4-methylcyclohexyl)oxy)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-N,N-dimethyl-3-(((R)-1,1,1-trifluoropropan-2-yl)oxy)benzamide

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SI-4381

4-((5-Chloro-4-(((1s,4S)-4-hydroxy-4-methylcyclohexyl)oxy)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-N,N-dimethyl-3-(((R)-1,1,1-trifluoropropan-2-yl)oxy)benzamide, >98% (HPLC)

CAS No. : [2364620-63-1]

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Chemical Properites
Mol. Formula :
C25H29ClF3N5O4
Mol. Weight :
555.98
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an orally bioavailable TTK inhibitor for the triple negative breast cancer (TNBC).

References : Riggs R. J. et al.: J. Med. Chem., 62(9), 4401-4410, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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