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4,5-Dihydro medroxyprogesterone (impurity F)

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4,5-Dihydro medroxyprogesterone (impurity F), >98%

CAS No. : [69688-15-9]

IUPAC Name : (5S,6S,8R,9S,10S,13S,14S,17R)-17-Acetyl-6,10,13-trimethyl-3-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate

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25MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
50MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
100MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
250MGRequest A Quote
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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C24H36O4
Mol. Weight :
388.55
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Medroxyprogesterone, which is a synthetic form of human progesterone that acts as an agonist at progesterone receptors and can be taken orally. It promotes cell proliferation via the PI3K/Akt signaling pathway and has been shown to inhibit atherosclerosis in mice. However, its progesterone agonist activity is less potent compared to medroxyprogesterone acetate.

References : Saitoh M. et al.: Endocrinology, 146(11), 4917-25, 2005; Ito F. et al.: J. Clin Endocrinol Metab., 99(6), 2188-97, 2014; Freudenberger T. et al.: Br. J. Pharmacol., 158(8), 1951-60, 2009; Yusop S. N. W. et al.: Steroids, 164:108735, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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