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4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline

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SL-7391

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline, >98%

CAS No. : [190728-25-7]

MDL No. : MFCD19685633

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
1G15.00
In Stock  Estimated to ship on 20 September 2026
5G45.00
In Stock  Estimated to ship on 20 September 2026
10G85.00
In Stock  Estimated to ship on 20 September 2026
25G195.00
In Stock  Estimated to ship on 20 September 2026
100G595.00
In Stock  Estimated to ship on 20 September 2026
We accept
Chemical Properites
Mol. Formula :
C17H16N2O3
Mol. Weight :
296.33
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of Cabozantinib and related analogs. Cabozantinib is an inhibitor of the tyrosine kinases c-Met and VEGFR2, and also inhibits AXL and RET. It is used to treat medullary thyroid cancer, renal cell carcinoma, and hepatocellular carcinoma.

References : You W. K. et al.: Cancer Res., 71(14), 4758-4768, 2011; Torres K. E. et al.: Clin Cancer Res., 17(12), 3943-3955, 2011; Yakes F. M. et al.: Mol Cancer Ther., 10(12), 2298-2308, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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