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4-Desfluoro-6-fluoro dolutegravir sodium

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4-Desfluoro-6-fluoro dolutegravir sodium, >98%

IUPAC Name : Sodium (4R,12aS)-9-((2,6-difluorobenzyl)carbamoyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazin-7-olate

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C20H18F2N3NaO5
Mol. Weight :
441.37
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Dolutegravir, which is a second-generation HIV integrase strand transfer inhibitor (INSTI). Dolutegravir is being developed for the treatment of HIV-1 infection in both adults and children.

References : Ding X. H. et al.: Bioorg. Med. Chem. 23(9), 1895-1922, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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