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4-Desmethyl 5-methyl vortioxetine

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SL-2464

4-Desmethyl 5-methyl vortioxetine, >98%

CAS No. : [508233-77-0]

IUPAC Name : 1-(2-((2,5-Dimethylphenyl)thio)phenyl)piperazine

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Chemical Properites
Mol. Formula :
C18H22N2S
Mol. Weight :
298.45
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : 4-Desmethyl 5-methyl vortioxetine is an analog of Vortioxetine, which is an inhibitor of 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT.

References : Bang-Andersen B. et al.: J. Med. Chem., 54(9), 3206-3221, 2011; Guilloux J. P. et al.: Neuropharmacology 73C, 147-159, 2013; Theunissen E. L. et al.: Clin Pharmacol Ther., 93(6), 493-501, 2013; Rothschild A. J. Eur Neuropsychopharmacol., 22(12), 858-66, 2012; Mark A. et al.: J. Pharmacol Exp Ther., 340(3), 666-75, 2012; Vieta. E. et al.: Eur Neuropsychopharm, 27(9), 877-884, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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