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4-Hydroxy estrone

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4-Hydroxy estrone, >98%

CAS No. : [3131-23-5]

Synonyms : 4-OHE1

IUPAC Name : (8R,9S,13S,14S)-3,4-Dihydroxy-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[a]phenanthren-17-one

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Chemical Properites
Mol. Formula :
C18H22O3
Mol. Weight :
286.37
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : 4-Hydroxy estrone is an estrone metabolite, provides strong neuroprotection against oxidative neurotoxicity. It enhances cytoplasmic translocation of p53 via SIRT1-mediated deacetylation and exhibits minimal estrogenic activity.

References : Hye J. C. et al.: Sci Rep., 10(1), 7283, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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