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4-Hydroxy nisoldipine

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SL-5116

4-Hydroxy nisoldipine, >98%

CAS No. : [106685-70-5]

Synonyms : 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-(2-hydroxy-2-methylpropyl) ester 5-methyl ester

IUPAC Name : 3-(2-Hydroxy-2-methylpropyl) 5-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C20H24N2O7
Mol. Weight :
404.42
Appearance :
Yellow solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a metabolite of Nisoldipine, which is a calcium channel blocker of the dihydropyridine class, used for the treatment of chronic angina pectoris and hypertension.

References : Morel N. et al.: Br. J. Pharmacol., 125(5), 1005-1012, 1998; Missan S. et al.: Br. J. Pharmacol., 140(5), 863-870, 2003; Sugawara H. et al.: Hypertens Res., 19(4), 223-228, 1996; Iimuro Y. et al.: Hepatology 24(2), 391-397, 1996; Splawski I. et al.: Cell 119(1), 19-31, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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