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4-Hydroxy propranolol-β-glucuronide

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4-Hydroxy propranolol-β-glucuronide, >98% (HPLC)

CAS No. : [94731-13-2]

Synonyms : 4-Hydroxy propranolol glucuronide

IUPAC Name : (2S,3S,5R,6S)-3,4,5-trihydroxy-6-((4-(2-hydroxy-3-(isopropylamino)propoxy)naphthalen-1-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid

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Chemical Properites
Mol. Formula :
C22H29NO9
Mol. Weight :
451.47
Appearance :
Pale brown solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : 4-Hydroxy propranolol-β-glucuronide is a metabolite of Propranolol, which induces apoptosis of human umbilical vein endothelial cells through down regulation of CD147 and it was the first successful beta blocker.

References : Xie W. et. al.: British Journal of Dermatology 168(4), 739, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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