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4'-Hydroxy tamoxifen

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SL-8979

4'-Hydroxy tamoxifen, >98%

CAS No. : [82413-23-8]

IUPAC Name : (Z)-4-(1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol

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Chemical Properites
Mol. Formula :
C26H29NO2
Mol. Weight :
387.52
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a metabolite of Tamoxifen, which is a selective estrogen receptor modulator (SERM). It is used in the treatment of breast cancer. It has also been explored as a valuable research compound in studies related to COVID-19.

References : Horwitz K. B. et al.: J. Biol Chem., 253(22), 8185-91, 1978; Rondon-Lagos M. et al:. Endocr Relat Cancer., 23(8), 635-50, 2016; Zheng A. et al.: Endocrinology 148(6), 2764-77, 2007; Reinert R. B. et al.: PLoS One 7(3), e33529, 2012; Osborne C. K. et al.: J. Clin Oncol., 18(17), 3172-86, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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