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4-Nitro apremilast impurity

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4-Nitro apremilast impurity, >98%

CAS No. : [253168-82-0]

Synonyms : rac-Apremilast impurity 19

IUPAC Name : 2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-4-nitroisoindoline-1,3-dione

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Chemical Properites
Mol. Formula :
C20H20N2O8S
Mol. Weight :
448.45
Appearance :
Yellow solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Apremilast, which is a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors.

References : Perez-Aso M. et al.: Arthritis Res Ther.,17, 249, 2015; Chen L. G. et al.: J. Chromatogr Sci., 54(8), 1336-40, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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