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4-O-Desmethyl 4-O-benzyl trimethoprim

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4-O-Desmethyl 4-O-benzyl trimethoprim, >98%

CAS No. : [21822-34-4]

IUPAC Name : 5-(4-(Benzyloxy)-3,5-dimethoxybenzyl)pyrimidine-2,4-diamine

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Chemical Properites
Mol. Formula :
C20H22N4O3
Mol. Weight :
366.42
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : 4-O-Desmethyl 4-O-benzyl trimethoprim is an analog of Trimethoprim, which is a bacteriostatic antibiotic. It is used mainly in the prophylaxis and treatment of urinary tract infections. 4-O-Desmethyl 4-O-ethyl trimethoprim also has potential antibacterial activity.

References : Laskowska E. et al.; Curr Microbiol., 47(4), 286-289, 2003; Brogden R. N. et al.; Drugs 23(6), 405-430, 1982; Rashid U. et al.: Bioorg. Med. Chem. Lett., 26(32), 5749-5753, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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