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(4S)-tert-Butyl 4-((5-chloropyridin-2-yl)thio)-3-hydroxy-3-(hydroxymethyl)pyrrolidine-1-carboxylate

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SI-2178

(4S)-tert-Butyl 4-((5-chloropyridin-2-yl)thio)-3-hydroxy-3-(hydroxymethyl)pyrrolidine-1-carboxylate, 97%

CAS No. : [2215841-89-5]

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
100MGRequest A Quote
Back Order  Estimated to ship on 01 November 2026
500MGRequest A Quote
Back Order  Estimated to ship on 01 November 2026
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Chemical Properites
Mol. Formula :
C15H21ClN2O4S
Mol. Weight :
360.86
Appearance :
Colorless oil
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of SI-2175 and related analogs, which is a transient receptor potential vanilloid‑4 (TRPV4) antagonist to treat pulmonary edema of heart failure patients.

References : Pero E. J. et al.: J. Med. Chem., 61(24),11209-11220, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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