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5-(1-Methylcyclopropoxy)-1H-indazole

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SI-1141

5-(1-Methylcyclopropoxy)-1H-indazole, 97%

CAS No. : [1626355-74-5]

MDL No. : MFCD31382069

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Chemical Properites
Mol. Formula :
C11H12N2O
Mol. Weight :
188.23
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key fragment in the preparation of MLi-2 and related analogs, which is a potent, highly selective, orally available, brain penetrant inhibitor of LRRK2.

References : Fell M. J. et al.: J. Pharmacol Exp Ther., 355(3), 397-409, 2015: Jack D. S. et al.: J. Med. Chem., 60(7), 2983-2992, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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