5-(3,5-Difluorobenzyl)-1H-indazol-3-amine

SI-2652

5-(3,5-Difluorobenzyl)-1H-indazol-3-amine, 97%

CAS No. : [1108745-30-7]

MDL No. : MFCD28129098

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
1G	40.00		Back Order	Estimated to ship on 04 October 2026
5G	185.00		Back Order	Estimated to ship on 04 October 2026
10G	325.00		Back Order	Estimated to ship on 04 October 2026

Applications : This is an advanced key intermediate in the preparation of Entrectinib and related analogs, which is a potent and orally available Trk, ROS1, and ALK inhibitor.

References : Menichincheri M. et al.: J. Med. Chem., 59(7), 3392-3408, 2016; Ardini E. et al.: Mol Cancer Ther., 15(4), 628-639, 2016; Rolfo C. et al.: Expert Opin Investig Drugs. 24(11),1493-1500, 2015; Russo M. et al.: Cancer Discov. 6(1), 36-44, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.