5-Azacytidine-15N4

SI-6677

5-Azacytidine-15N4, >98% (HPLC)

CAS No. : [2139283-40-0]

Synonyms : Azacitidine-15N4; 5-AzaC-15N4; Ladakamycin-15N4

IUPAC Name : 4-(Amino-15N)-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one-1,3,5-15N3

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : 5‑Azacytidine‑¹⁵N₄ is a stable‑isotope‑labelled version of 5‑Azacytidine, used for mechanistic and tracing applications. 5‑Azacytidine inhibits DNA methylation by incorporating into DNA and irreversibly trapping DNMTs, leading to epigenetic reactivation. It also triggers autophagy as part of its cellular response.

References : Russak E. M. et al.: Ann. Pharmacother., 53(2), 211-216, 2019; Li L. H. et al.: Cancer Res., 30(11), 2760-9, 1970; Christman J. K. Oncogene., 21(35), 5483-95, 2002; Creusot F. et al.: J. Biol. Chem., 257(4), 2041-8, 1982; Li L. H. et al.: Cancer Res., 30(11), 2760-9, 1970; Marycz K. et al.: Oxid. Med. Cell Longev., 2019, 1523140, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.