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5'-Deoxyuridin-4'-ene

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SI-4451

5'-Deoxyuridin-4'-ene, 97%

CAS No. : [14365-63-0]

MDL No. : MFCD23160105

IUPAC Name : 1-((2R,3R,4S)-3,4-Dihydroxy-5-methylenetetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

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Chemical Properites
Mol. Formula :
C9H10N2O5
Mol. Weight :
226.19
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of Adafosbuvir related analogs, which is a potent inhibitior of hepatitis C virus (HCV) NS5B polymerase.

References : Wang G. et al.: J. Med. Chem., 62(9), 4555-4570, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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