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5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile

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SI-1373

5-Fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile, 97%

CAS No. : [1350653-26-7]

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
1G45.00
Back Order  Estimated to ship on 20 September 2026
5G155.00
Back Order  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C14H8F2N4
Mol. Weight :
270.24
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of Vericiguat and related analogs, which is a soluble guanylate cyclase stimulator (sGC) for the treatment of chronic heart failure.

References : Follmann M. et al.: J. Med. Chem., 60(12), 5146-5161, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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