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5-O-Desmethyl donepezil

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SL-4449

5-O-Desmethyl donepezil, >98%

CAS No. : [120013-57-2]

IUPAC Name : 2-((1-Benzylpiperidin-4-yl)methyl)-5-hydroxy-6-methoxy-2,3-dihydro-1H-inden-1-one

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C23H27NO3
Mol. Weight :
365.47
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : 5-O-Desmethyl donepezil is an impurity of Donepezil, which is a piperidine based, potent, specific, non-competitive and reversible inhibitor of acetylcholinesterase (AChE), used for the treatment of mild to moderate dementia of the alzheimer's type.

References : Ramon C. Neuropsychiatr Dis Treat., 3(3), 303-333, 2007; Miki A. et al.: Curr Eye Res., 31(1), 69-77, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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