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(5R,6R)-5-(5-Bromo-2-fluorophenyl)-5-methyl-6-(trifluoromethyl)-5,6-dihydro-2H-1,4-oxazin-3-amine

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SI-985

(5R,6R)-5-(5-Bromo-2-fluorophenyl)-5-methyl-6-(trifluoromethyl)-5,6-dihydro-2H-1,4-oxazin-3-amine, 97%

CAS No. : [1443259-49-1]

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100MGRequest A Quote
Back Order  Estimated to ship on 01 November 2026
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Back Order  Estimated to ship on 01 November 2026
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Chemical Properites
Mol. Formula :
C12H11BrF4N2O
Mol. Weight :
355.13
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced intermediate in the preparation of SI-983 and related analogs, which is a β‑secretase 1 (BACE1) inhibitor.

References : Gijsen J. M. H. et al.: J. Med. Chem., 61(12), 5292-5303, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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