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(5R,7S)-7-(6-Oxo-5,6,7,8-tetrahydronaphthalen-2-yl)-3-oxa-1-azaspiro[4.4]nonan-2-one

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SI-3450

(5R,7S)-7-(6-Oxo-5,6,7,8-tetrahydronaphthalen-2-yl)-3-oxa-1-azaspiro[4.4]nonan-2-one, 97%

CAS No. : [1622180-55-5]

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100MGRequest A Quote
Back Order  Estimated to ship on 01 November 2026
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Back Order  Estimated to ship on 01 November 2026
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Chemical Properites
Mol. Formula :
C17H19NO3
Mol. Weight :
285.34
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of BMS-986166 and related analogs, which is a potent, selective sphingosine-1-phosphate (S1P) receptor modulator for the treatment of ulcerative colitis.

References : Gilmore L. J. et al.: J. Med. Chem., 62(5), 2265-2285, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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