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6-(4-Chloro-5-fluoropyrimidin-2-yl)-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

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6-(4-Chloro-5-fluoropyrimidin-2-yl)-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole, >98%

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
10MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
25MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
50MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C15H13ClF2N4
Mol. Weight :
322.74
Appearance :
Solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the synthesis of Abemaciclib and related analogs. Abemaciclib is a selective CDK4/6 inhibitor and can be used for the treatment of breast cancer.

References : Ku B. M. et al.: Oncotarget., 7(12), 14803-13, 2016; Yadav V. et al.: Mol Cancer Ther., 13(10), 2253-63, 2014; Gelbert L. M. et al.: Invest New Drugs., 32(5), 825-37, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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