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6-beta-Hydroxybudesonide

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SL-5322

6-beta-Hydroxybudesonide, >98%

CAS No. : [88411-77-2]

Synonyms : (6β,11β,16α)-16,17-[Butylidenebis(oxy)]-6,11,21-trihydroxypregna-1,4-diene-3,20-dione

IUPAC Name : (2R,6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-2,7-Dihydroxy-8b-(2-hydroxyacetyl)-6a,8a-dimethyl-10-propyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one

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Chemical Properites
Mol. Formula :
C25H34O7
Mol. Weight :
446.54
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a metabolite of Budesonide, which is a glucocorticoid steroid for the treatment of asthma, non-infectious rhinitis.

References : Stellato C. et al.: J. Immunol., 163(10), 5624-5632, 1999; Bandi N. et al.: Eur J. Pharmacol., 425(2), 109-116, 2001; Ek A. et al.: Allergy 54(7), 691-699, 1999; Jansson A. H. et al.: Vascul Pharmacol., 43(2), 101-111, 2005; Yao R. et al.: Oncogene 23(46), 7746-7752, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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