6-Bromo-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidine-2,7(3H,8H)-dione

SL-8696

6-Bromo-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidine-2,7(3H,8H)-dione, >98%

Synonyms : Palbociclib impurity 22

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
100MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
250MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
500MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : This is an advanced key intermediate in the synthesis of Palbociclib, which is a selective CDK4 and CDK6 inhibitor. Palbociclib is used for the treatment of ER-positive and HER2-negative breast cancer.

References : Fry D. W. et al.: Mol Cancer Ther., 3(11), 1427-1438, 2004; Katsumi Y. et al.: Biochem Biophys Res Commun, 413(1), 62-68, 2011; Goel S. et al.: Nature 548(7668), 471-475, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.