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6-Raloxifene-β-D-glucopyranoside

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SL-3825

6-Raloxifene-β-D-glucopyranoside, >98%

CAS No. : [334758-18-8]

Synonyms : [6-​(β-​D-​Glucopyranosyloxy)​-​2-​(4-​hydroxyphenyl)​benzo[b]​thien-​3-​yl]​[4-​[2-​(1-​piperidinyl)​ethoxy]​phenyl]​-methanone

IUPAC Name : (2-(4-Hydroxyphenyl)-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)benzo[b]thiophen-3-yl)(4-(2-(piperidin-1-yl)ethoxy)phenyl)methanone

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Chemical Properites
Mol. Formula :
C34H37NO9S
Mol. Weight :
635.72
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : 6-Raloxifene-β-D-glucopyranoside is an analog of Raloxifene, which is a second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women.

References : Obach R. S. et al.: Drug Metab Dispos., 32(1), 89-97, 2004; Yang N. N. et al.: Endocrinology., 137(5), 2075-2084, 1996; Black L. J. et al.: J. Clin Invest., 93(1), 63-69, 1994; Evans G. et al.: Endocrinology, 134(5), 2283-2288, 1994; Sato M. et al.: FASEB J, 10(8), 905-912, 1996.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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