6-(((S)-1-(5-Fluoropyridin-2-yl)ethyl)amino)-1-(3-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde

SI-4611

6-(((S)-1-(5-Fluoropyridin-2-yl)ethyl)amino)-1-(3-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde, 97%

CAS No. : [2364447-59-4]

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Applications : This is an advanced key intermediate in the preparation of ALK-IN-5 related analogs, which is a potent, selective, and brain-penetrant anaplastic lymphoma kinase (ALK) inhibitor.

References : Fushimi M. et al.: J. Med. Chem., 62(10), 4915-4935, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.