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6-tert-Butyl 5-ethyl 2-hydroxy-7,8-dihydro-1,6-naphthyridine-5,6(5H)-dicarboxylate

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SI-940

6-tert-Butyl 5-ethyl 2-hydroxy-7,8-dihydro-1,6-naphthyridine-5,6(5H)-dicarboxylate, 97%

CAS No. : [1644236-90-7]

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Back Order  Estimated to ship on 04 October 2026
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C16H22N2O5
Mol. Weight :
322.36
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced naphthyridine key intermediate in the preparation of TAK-828F and related analogs, which is a potent and selective orally available RORγt inverse agonist.

References : Kono M. et al.: J. Med. Chem., 61(7), 2973-2988, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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