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6a-Methylprednisone 21-acetate

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6a-Methylprednisone 21-acetate, >98%

CAS No. : [115321-98-7]

Synonyms : 17-hydroxy-6a-methyl-3,11,20-trioxopregna-1,4-dine-21-yl acetate; Methylprednisolone acetate EP impurity K

IUPAC Name : 2-((6S,8S,9S,10R,13S,14S,17R)-17-Hydroxy-6,10,13-trimethyl-3,11-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C24H30O6
Mol. Weight :
414.5
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Methylprednisolone, which is a synthetic corticosteroid that helps reduce inflammation and modulate the immune system. It may improve severe or critical COVID-19 cases by activating ACE2 and lowering IL-6 levels.

References : Strupp M. et al.: N. Engl J. Med., 351(4), 354-61, 2004; Bracken M.B. et al.: N. Engl J. Med., 322(20), 1405-11, 1990; Zhen X. et al.: Int. J. Biol Sci., 16(13), 2382-2391, 2020; Fan Y. et al.: Bone Res., 13(1), 18, 2025; Yu R. et al.: Drug Metab Dispos., 52(7), 662-672, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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