7-Chloro-4-(4-hydroxyanilino)quinoline

SL-5025

7-Chloro-4-(4-hydroxyanilino)quinoline, >98%

CAS No. : [81099-86-7]

Synonyms : p-[(7-Chloro-4-quinolyl)amino]phenol; 7-Chloro-4-p-hydroxyanilinoquinoline; NSC 12488; NSC 130792

IUPAC Name : 4-((7-Chloroquinolin-4-yl)amino)phenol

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Applications : This is an impurity of Amodiaquine, which is an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties.

References : Yokoyama A. et al.: Eur J. Pharmacol, 558(1-3), 179-84, 2007; Horton J. R. et al.: J. Mol Biol, 353(2), 334-344, 2005; Barth H. et al.: Br. J. Pharmacol, 55(3), 321-327, 1975.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.