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7-Epi lincomycin hydrochloride

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SL-10902

7-Epi lincomycin hydrochloride, >98%

CAS No. : [26389-84-4]

IUPAC Name : (2S,4R)-N-((1R,2S)-2-Hydroxy-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-1-methyl-4-propylpyrrolidine-2-carboxamide hydrochloride

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Chemical Properites
Mol. Formula :
C18H34N2O6S • HCl
Mol. Weight :
443
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Lincomycin, an antibiotic. Lincomycin impacts protein, RNA, and DNA synthesis in Act. Roseolus. It inhibits protein synthesis mainly in Gram-positive bacteria by binding to the 50S ribosomal subunit and disrupting aminoacyl-tRNA binding and transpeptidation; it also affects Gram-negative bacteria to a lesser degree.

References : Griaznova N. S. et al.: Antibiotiki., 25(4), 250-256, 1980; Hummel H. W. et al.: Mol Gen Genet., 169(3), 345-347, 1979; Champney W. S. et al.: Curr Microbiol., 41(2), 126-135, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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