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7-Hydroxy fluphenazine-d8

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SL-2230

7-Hydroxy fluphenazine-d8, >98% (CP)

Isotopic Purity : 98 atom % D

CAS No. : [1285980-02-0]

Related CAS No. : [33098-48-5] of the unlabelled compound

Synonyms : 4-[3-[7-Hydroxy-2-(trifluoromethyl)phenothiazin-10-yl]propyl]-1-piperazine-d8-ethanol; SQ 11426-d8

IUPAC Name : 10-[3-[4-(2-Hydroxyethyl)-1-piperazinyl-d8-]propyl]-8-(trifluoromethyl)-10H-phenothiazin-3-ol

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Chemical Properites
Mol. Formula :
C22H18D8F3N3O2S
Mol. Weight :
461.57
Appearance :
Pale brown solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : 7-Hydroxy fluphenazine-d8 is a deuterium labelled version metabolite of Fluphenazine, which is a phenothiazine-class D1DR and D2DR inhibitor; used to deliver Fluphenazine to biological systems in studies probing the effects and metabolic fates of this commonly used dopamine antagonist.

References : Trzeciak H. I. et al.: Arzneimittelforschung 26(9), 1697-700, 1976; Whelpton R. Curry S. H. J. Pharm. Pharmacol., 28(12), 869-873, 1976; Javaid J. I. et al.: J. Chromatogr Sci.,19(9), 439-443, 1981.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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