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8-(3-Chloro-5-(trifluoromethyl)pyridin-4-yl)-2,8-diazaspiro[4.5]decan-1-one

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SI-2327

8-(3-Chloro-5-(trifluoromethyl)pyridin-4-yl)-2,8-diazaspiro[4.5]decan-1-one, 97%

CAS No. : [1858249-09-8]

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100MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C14H15ClF3N3O
Mol. Weight :
333.74
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of CCT-251921 and related analogs, which is a potent, selective, and orally bioavailable CDK8 inhibitor.

References : Mallinger A. et al.: J. Med. Chem., 59(3), 1078-1101,2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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