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A-1210477

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SI-3803

A-1210477, >98% (HPLC)

CAS No. : [1668553-26-1]

MDL No. : MFCD28399118

IUPAC Name : 7-(5-((4-(4-(N,N-Dimethylsulfamoyl)piperazin-1-yl)phenoxy)methyl)-1,3-dimethyl-1H-pyrazol-4-yl)-1-(2-morpholinoethyl)-3-(3-(naphthalen-1-yloxy)propyl)-1H-indole-2-carboxylic acid

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Chemical Properites
Mol. Formula :
C46H55N7O7S
Mol. Weight :
850.05
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : A-1210477 is a potent and selective inhibitor of MCL-1 with a Ki of 0.45 nM.

References : Bruncko M. et al.: J. Med. Chem, 58(5), 2180-2194, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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