A-317491 sodium salt hydrate

SI-7652

A-317491 sodium salt hydrate, >98% (HPLC)

IUPAC Name : (S)-5-((3-Phenoxybenzyl)(1,2,3,4-tetrahydronaphthalen-1-yl)carbamoyl)benzene-1,2,4-tricarboxylic acid, sodium salt hydrate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : A‑317491 sodium salt hydrate selectively antagonizes P2X₃ and P2X_2/3 receptors with nanomolar affinity (K_i= 9–92 nM) and shows minimal activity at other P2 receptors or unrelated molecular targets. By blocking P2X₃/P2X_2/3‑mediated calcium influx, it effectively reduces inflammatory and neuropathic pain responses, making it a valuable tool for studying purinergic nociception.

References : Jarvis M. F. et al.: Proc. Natl. Acad. Sci. U S A, 99(26), 17179-84, 2002; Wu G. et al.: Eur. J. Pharmacol., 504(1-2), 45-53, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.