A-484954

SI-6704

A-484954, >98% (HPLC)

CAS No. : [142557-61-7]

IUPAC Name : 7-Amino-1-cyclopropyl-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : A‑484954 selectively inhibits eEF2K with an IC₅₀ of 280 nM, providing a useful chemical probe for studying eEF2K‑dependent regulation of protein synthesis and cellular stress pathways.

References : Chen Z. et al.: J. Biol. Chem., 286(51), 43951-8, 2011; Kodama T. et al.: J. Pharmacol. Sci., 137(1), 86-92, 2018; Kameshima S. et al.: Am. J. Physiol. Heart Circ. Physiol., 308(10), H1298-305, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.