A419259

SI-6481

A419259, >98% (HPLC)

CAS No. : [364042-47-7]

Synonyms : RK-20449

IUPAC Name : 7-((1r,4r)-4-(4-Methylpiperazin-1-yl)cyclohexyl)-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Price And Availability
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5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : A419259 selectively targets Src‑family kinases, showing low‑nanomolar inhibition of Src (IC₅₀ = 9 nM) and potent sub‑3 nM inhibition of Lck and Lyn. Its activity profile makes it valuable for probing Src‑dependent pathways.

References : Wilson M. B. et al.: Oncogene., 21(53), 8075-88, 2002; Zhang X. et al.: Stem Cell Res., 13(3 Pt A), 379-89, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.