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A419259 trihydrochloride

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SI-6482

A419259 trihydrochloride, >98% (HPLC)

CAS No. : [1435934-25-0]

Synonyms : RK-20449 trihydrochloride

IUPAC Name : 7-((1r,4r)-4-(4-Methylpiperazin-1-yl)cyclohexyl)-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine trihydrochloride

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Chemical Properites
Mol. Formula :
C29H34N6O • 3HCl
Mol. Weight :
592
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : A419259 trihydrochloride selectively targets Src‑family kinases, inhibiting Src at 9 nM and Lck/Lyn at 3 nM. Its activity profile supports its use in studies of Src‑mediated signaling and cellular responses.

References : Wilson M. B. et al.: Oncogene., 21(53), 8075-88, 2002; Zhang X. et al.: Stem Cell Res., 13(3 Pt A), 379-89, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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