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SI-5951

A86, >98% (HPLC)

CAS No. : [2079069-01-3]

IUPAC Name : (1r,4r)-N1-(4-(5-(Cyclopropylmethyl)-1-methyl-1H-pyrazol-4-yl)-5-fluoropyrimidin-2-yl)cyclohexane-1,4-diamine

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Chemical Properites
Mol. Formula :
C18H25FN6
Mol. Weight :
344.44
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : A86 is a potent and orally active casein kinase 1α (CK1α) inhibitor. A86 induces leukemia cell apoptosis, and has potent anti-leukemic activities.

References : Minzel W. et al.: Cell 175(1), 171-185.e25, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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