AAK1 inhibitor

SI-7009

AAK1 inhibitor, >98% (HPLC)

IUPAC Name : Methyl (S)-(5-((2-amino-2,4-dimethylpentyl)oxy)-6-methyl-[2,4'-bipyridin]-2'-yl)carbamate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This compound is a highly selective and potent AAK1 inhibitor with strong drug‑like properties. It demonstrated robust efficacy in two neuropathic pain rat models and showed excellent CNS penetration with clear spinal cord target engagement. In addition, it exhibited favorable physicochemical characteristics and oral pharmacokinetic (PK) properties, supporting its potential as a promising therapeutic candidate for neuropathic pain research.

References : Luo G. et al.: J. Med. Chem., 65(6), 4534−4564, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.