AB-452

SI-7532

AB-452, >98% (HPLC)

CAS No. : [2226178-35-2]

IUPAC Name : (S)-6-Isopropyl-2-methoxy-3-(3-methoxypropoxy)-10-oxo-5,10-dihydro-6H-pyrido[1,2-h][1,7]naphthyridine-9-carboxylic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : AB‑452 is an orally active DHQ‑based inhibitor of PAPD5/7 that promotes HBV RNA destabilization. Its strong in vitro activity and significant antiviral effects in chronic HBV mouse models support its use in studies of HBV RNA metabolism and host‑directed antiviral strategies.

References : Gotchev D. et al.: J. Med. Chem., 67(2), 1421-1446, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.