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ABBV-712

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SI-7393

ABBV-712, >98% (HPLC)

CAS No. : [2368945-27-9]

IUPAC Name : (R)-N-(3-(4-(Methoxymethyl)-6-(3-methoxytetrahydrofuran-3-yl)pyridin-2-yl)-1-(oxetan-3-yl)-1H-pyrrolo[2,3-c]pyridin-5-yl)acetamide

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Chemical Properites
Mol. Formula :
C24H28N4O5
Mol. Weight :
452.51
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : ABBV‑712 selectively targets TYK2 with submicromolar potency, including EC50 values of 0.01 µM (JH2), 0.19 µM (cellular), and 0.17 µM (whole blood). It demonstrates robust anti‑inflammatory effects and serves as a valuable tool for investigating TYK2‑driven autoimmune diseases.

References : Breinlinger E. et al.: J. Med. Chem., 66(20), 14335-14356, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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