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ABBV-744

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SI-6060

ABBV-744, >98% (HPLC)

CAS No. : [2138861-99-9]

IUPAC Name : N-Ethyl-4-(2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide

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Chemical Properites
Mol. Formula :
C28H30FN3O4
Mol. Weight :
491.56
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : ABBV-744 is a first‑in‑class, orally active BDII‑selective BET inhibitor (IC50 = 4–18 nM) with favorable drug‑like properties.

References : Faivre E. J. et al.: Nature, 578(7794), 306-310, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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