Abemaciclib

SI-5442

Abemaciclib, >98% (HPLC)

CAS No. : [1231929-97-7]

MDL No. : MFCD22665744

Synonyms : LY-2835219

IUPAC Name : N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
1G	85.00		In Stock	Estimated to ship on 20 September 2026
5G	275.00		In Stock	Estimated to ship on 20 September 2026
10G	475.00		In Stock	Estimated to ship on 20 September 2026
25G	955.00		In Stock	Estimated to ship on 20 September 2026

Applications : Abemaciclib is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively. It can be used for the treatment of breast cancer.

References : Ku B. M. et al.: Oncotarget., 7(12), 14803-13, 2016; Yadav V. et al.: Mol Cancer Ther., 13(10), 2253-63, 2014; Gelbert L. M. et al.: Invest New Drugs., 32(5), 825-37, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.