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Abemaciclib-d8 metabolite M18

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SI-5448

Abemaciclib-d8 metabolite M18, >98% (HPLC)

Isotopic Purity : 98 atom % D

Synonyms : LSN-3106729-d8

IUPAC Name : (4-Fluoro-6-(5-fluoro-2-((5-((piperazin-1-yl-d8)methyl)pyridin-2-yl)amino)pyrimidin-4-yl)-1-isopropyl-1H-benzo[d]imidazol-2-yl)methanol

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
10MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Note: Abemaciclib-d8 metabolite M18is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C25H20D8F2N8O
Mol. Weight :
502.60
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version of Abemaciclib metabolite M18. Abemaciclib is a selective CDK4/6 inhibitor. Abemaciclib can be used for the treatment of breast cancer.

References : Ku B. M. et al.: Oncotarget., 7(12), 14803-13, 2016; Yadav V. et al.: Mol Cancer Ther., 13(10), 2253-63, 2014; Gelbert L. M. et al.: Invest New Drugs 32(5), 825-37, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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