Abemaciclib mesylate

SI-5445

Abemaciclib mesylate, >98% (HPLC)

CAS No. : [1231930-82-7]

MDL No. : MFCD25562906

Synonyms : LY-2835219 methanesulfonate

IUPAC Name : N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine methanesulfonate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
1G	85.00		Back Order	Estimated to ship on 04 October 2026
5G	285.00		Back Order	Estimated to ship on 04 October 2026
10G	485.00		Back Order	Estimated to ship on 04 October 2026
25G	995.00		Back Order	Estimated to ship on 04 October 2026

Applications : Abemaciclib mesylate is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively. It can be used for the treatment of breast cancer.

References : Ku B. M. et al.: Oncotarget., 7(12), 14803-13, 2016; Yadav V. et al.: Mol Cancer Ther., 13(10), 2253-63, 2014; Gelbert L. M. et al.: Invest New Drugs 32(5), 825-37, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.