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Abemaciclib metabolite M18 hydrochloride

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SI-5447

Abemaciclib metabolite M18 hydrochloride, >98% (HPLC)

CAS No. : [2704316-82-3]

Synonyms : Hydroxy-N-desethylabemaciclib hydrochloride; LSN-3106729 hydrochloride

IUPAC Name : (4-Fluoro-6-(5-fluoro-2-((5-(piperazin-1-ylmethyl)pyridin-2-yl)amino)pyrimidin-4-yl)-1-isopropyl-1H-benzo[d]imidazol-2-yl)methanol hydrochloride

Price And Availability
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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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500MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Note: Abemaciclib metabolite M18 hydrochloride is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C25H28F2N8O . HCl
Mol. Weight :
531.01
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a metabolite of Abemaciclib, which is a selective CDK4/6 inhibitor. Abemaciclib can be used for the treatment of breast cancer.

References : Ku B. M. et al.: Oncotarget., 7(12), 14803-13, 2016; Yadav V. et al.: Mol Cancer Ther., 13(10), 2253-63, 2014; Gelbert L. M. et al.: Invest New Drugs 32(5), 825-37, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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